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Myopia or nearsightedness is the most common reason for the development of impaired vision and visual disability. with a high prevalence around the globe, it has been investigated that among all the visual disabilities myopia is prevailing most rapidly with no discrimination of age and gender. Similarly, estimations have provided the evidence that about 4 billion people are affected from this disease in Pakistan. Myopic families from population of Pakistan were identified and were analyzed by microsatellite marker designed specifically for this disease. Genotypic analysis including Linkage...

Myopia is a refractive abnormality of the eye in which the parallel light rays from an object at optical infinity are focused by the eye in front of the retina rather than on it. This is the first experimental study on Myopia in Pakistan because this disease is spreading here day by day with prevalence rate of 36.5%. Microsatellite markers have been proved as an efficient and powerful tool for discovering any diseased locus. So a panel of these markers was used in this study. Blood samples of various myopic families were collected from various areas of Punjab and their DNA was...