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Diabetes mellitus describes as heterogeneous disease caused by a combination of inherited and acquired deficiency in secretion of insulin and by reduced sensitivity of the tissues to secreted insulin. The number of people with diabetes is increasing owing to population growth, ageing, and sedentary lifestyle. Current medicine despite the efficacy showed wide range of side effects, which itself increases the annual rate of morbidity and mortality of diabetes mellitus. In this circumstance there is urge for novel medicine with lower adverse effect. Standardized natural product that derived from...