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Solid dispersion technology has proved to be a powerful technique in the field of drug delivery of poorly water soluble drugs by enhancing the dissolution rate and bioavailability of that drug. Here we used four drugs namely Spironolactone, Etoricoxib, Ibuprofen and Carvedilol. Solid dispersions were prepared by solvent co-precipitation method, where acetone was used as solvent and pet-ether was used as anti solvent. Different water soluble polymer (HPMC 6cps, Kollicoat IR, Kollidon VA 64 and HPC), and as an excipient poloxamer were used to prepare solid dispersion. Paddle type dissolution...

A drug's efficiency may be affected by the degree to which it binds to the proteins within blood plasma. The less bound a drug is, the more efficiently it can traverse cell membranes or diffuse. The research regarding protein binding of the drugs has been accomplished in the Department of Pharmacy, University of Asia Pacific (UAP), Dhaka, Bangladesh. The department is continuing its research activities since its inception in different fields, likely, Pharmaceutical Technology, Pharmaceutical Microbiology, Pharmaceutical Biotechnology, Phytochemistry etc. Every year a number of research...

The effect of Proteinase-k on extracted genomic DNA of gram positive strains were tried to know here and found that Bacillus cereus and Staphylococcus aureus had significant effect where as Bacillus subtilis did not show any major impact on total DNA concentration. The research has been done in the Department of Pharmacy, University of Asia Pacific, Dhaka, Bangladesh. The department is continuing its research activities since its inception in different fields likely Pharmaceutical Technology, Pharmaceutical Microbiology, Pharmaceutical Biotechnology, Phytochemistry etc. Every year a number of...