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Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and increased susceptibility to fracture. Epidemiological studies showed higher frequency of osteoporosis in diabetic patients as compared with sex and age matched control. Bone mineral density and other biochemical markers of bone turnover are very much affected in diabetic rats. Reduced bone mass, occurring with increased frequency in diabetes mellitus, has been attributed to poor glycemic control. Insulin deficiency in diabetes leads to this complication....