Chemoselective Nucleophilic α-Amination of Amides

ISBN-13: 9783658300197 / Angielski / Miękka / 2020 / 60 str.

Miran Lemmerer

Spis treści

Traditional Umpolung Reactions in Organic Chemistry.- Insight into Electrophilic Amide Activation.- Results and Discussion of a New α-Amination Method via Umpolung of Amides.- α-Arylation of Carbonlys via a Smiles Rearrangement.

O autorze

Miran Lemmerer is currently pursuing his PhD studies under supervision of Prof. Dr. Nuno Maulide at the Department of Organic Chemistry, University of Vienna, Austria. 

Blurb

α-Amino carbonyl compounds are omnipresent in all living organisms, making their selective synthesis highly sought after. However, the synthesis of α-amino amides, a subclass of α-amino carbonyls, in the presence of other carbonyls is usually challenging, due to the required harsh conditions. Miran Lemmerer expands a novel chemoselective approach for the synthesis of these intriguing molecules together with Univ.-Prof. Dr. Nuno Maulide’s team.

Contents

• Traditional Umpolung Reactions in Organic Chemistry
• Insight into Electrophilic Amide Activation
• Results and Discussion of a New α-Amination Method via Umpolung of Amides
• α-Arylation of Carbonlys via a Smiles Rearrangement

Target Groups

Scientists and students in the field of organic chemistry, especially in methodology development

The Author

Miran Lemmerer is currently pursuing his PhD studies under supervision of Prof. Dr. Nuno Maulide at the Department of Organic Chemistry, University of Vienna, Austria.