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It is now becoming very clear that the development and progression of tumor towards the malignant (metastatic) phenotype depends tightly on the interaction between the tumor cells and the tumor microenvironment. Tumor cells respond to stimuli generated within the tumor microenvironment for their growth advantage while the tumor cell themselves reshape and remodel the architecture and function of their extracellular matrices. The term tumor microenvironment is a wide umbrella consisting of stromal cells such as fibroblasts and endothelial cells and infiltration immune cells including T and...

It is now becoming very clear that the development and progression of tumor towards the malignant (metastatic) phenotype depends tightly on the interaction between the tumor cells and the tumor microenvironment. Tumor cells respond to stimuli generated within the tumor microenvironment for their growth advantage while the tumor cell themselves reshape and remodel the architecture and function of their extracellular matrices. The term tumor microenvironment is a wide umbrella consisting of stromal cells such as fibroblasts and endothelial cells and infiltration immune cells including T and...

Attah, v'HaLevy, v'HaGeir is an eclectic compilation of divrei Torah based on the parashat hashavuah.

Over an eighteen year period, on a weekly basis, Menashe Frank recorded at least one interesting,

provocative or inspirational d'var Torah that he heard or read. Contributors range from close personal

friends to the greatest Torah scholars in history. His handwritten notes eventually filled an entire three-

ring binder. On the occasion of his son becoming a Bar Mitzvah, Frank, applying his unique life-

perspective and the guidance of his Rabbi, has...