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In Running With Ghosts, author Matt Tullis reminds us that surviving childhood cancer can be a challenge as formidable as fighting for your life—and more enduring. The eldest of three sons born to a trucker and an office-worker, who lived in the idyllic village of Apple Creek, Ohio, Tullis was diagnosed with acute lymphoblastic leukemia at age 15. In short order, the sports-mad teenager found himself on the cancer ward of Akron Children’s Hospital. One of the lucky ones, he walked out and kept on going.

Years later, as a journalist and college professor,...