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The clinical and experimental effects of cytokines have been realized for a long time. The clinical effects of tumor necrosis factor were noted almost 100 years ago. The basic biological effects of interferons and the hemopoietic growth factors have been known for more than 20 years. Given the basis of modern molecular biotechniques, information concern- ing the mediators of cellular interactions is expanding almost exponentially. New principles in the regulation of cell growth, microenvironment, immune response, and malignancy are being discoverd right now. New therapeutic options are...

Covering a wide range of recent research developments, from basic research to clinical applications, this volume provides an overview of the biological role of cytokines as well as experiments with new cytokines. It should benefit immunologists who are developing therapeutic methods.