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The author of SAINT returns with a new novel about Lotte Keene, a biological detective who has had enough of government bureaucracy at the Centers for Disease Control (CDC) and resigns, but can never escape. After surviving the outbreak of a mysterious pathogen in the Amazonian jungle, Keene returns home and is pulled into the seemingly infinite mystery of a new, more malignant killer in the Sierra Nevada Mountains. There for the first time in her forensic biology career she confronts a pathogen so potent and lethal that it seems unnatural. She also discovers secrets in the forested mountains...

An experiment 2,000 years in the making. Biogeneticist Andrew Shepard resurrects the memory of an ancient in a living human subject. Simon Peter is reborn. For the world's political and spiritual leaders, it is a crisis. For the faithful, it is a miracle. For humankind, this changes everything. Peter escapes from the BioGenera lab in a desperate attempt to return to Rome and to confront the Pontiff, while being stalked by a mysterious assassin intent on silencing him once and for all.