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Large artery stiffness is predictive of adverse cardiovascular events and all cause mortality.
This book presents a series of in-vivo experimental studies investigating effects of structural and functional changes on large artery stiffness. Novel analysis methods for measurement of arterial stiffness indexes are discussed and applied.
Findings in acute inflammation, active and passive changes in systemic pressure, aortic elastic laminae defects, aortic calcification, and vasoconstrictor agents (angiotensin-II, noradrenaline, and endothelin-1) in animal models are reported. The vasodilating...