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Melanotransferrin (melanoma tumour antigen p97) is an
iron-
binding transferrin homologue expressed at high
levels on
melanoma tumours and at lower levels on normal
tissues. Unlike its
relatives, transferrin and lactoferrin,
melanotransferrin is
membrane-bound. These properties suggest that
melanotransferrin
may assist melanoma and other tumour cell types with
their increased requirement for iron. To address this
hypothesis we
utilised models including: (i) the melanotransferrin
knockout mouse, and (ii) systematic down-regulation of
melanotransferrin in melanoma cells using...

Louise Dunn is a life coach, minister, speaker, and retreat facilitator. In her coaching work, she specializes in helping people find their soul's purpose, with the ultimate goal of turning their personal and professional dreams into reality. She also leads women's groups around the themes of healing and transformation. Louise brings a deeply compassionate and joyous spirit to her clients and students. Her work as a minister has greatly influenced her sensitive response to people in grief and life transitions. www.LouiseDunn.com

Deb Buehler is a professional writer, writing coach, and bee...