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Patients with cancer can suffer from a bewildering variety of neurologic signs and symptoms. The neurologic symptoms are often more disabling than the primary cancer. Symptoms including confusion, seizures, pain and paralysis may be a result of either metastases to the nervous system or one of several nonmetastatic complications of cancer. The physician who promptly recognizes neurologic symptoms occurring in a patient with cancer and makes an early diagnosis may prevent the symptoms from becoming permanently disabling or sometimes lethal. This monograph, an update of the first edition...

Lymphoma and leukemia of the nervous system may be defined as direct or indirect involvement of the central or peripheral nervous systems by these malignancies. The diagnosis and management of these conditions is the subject of this book. In the first part of the book the focus is on primary central nervous system lymphoma (PCNSL), an uncommon type of non-Hodgkin lymphoma confined to the nervous system. The first two chapters of the book are an overview of the lymphoid malignancies and leukemias for non-oncologists. This introduction is followed by chapters on the pathology, epidemiology,...