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Reviews the impact of recombinant DNA technology on the study of proteins that are essential for hemostasis and thrombosis. The 18 papers discuss the characterization of the relevant gene and protein structures, molecular defects affecting hemostasis, the production of proteins by recombinant techno

Recent progress in molecular biology has led to a rapid expansion of our understanding of the proteins that are essential for hemostasis and thrombosis. The goal of the XXI Annual Scientific Symposium of the American Red Cross was to provide a forum to explore and document the impact of recombinant DNA technology in this field. The speakers described the essential features of the genes responsible for key plasma proteins important in hemostasis, including procoagulant Factors VIII and IX and anticoagulant proteins, Antithrombin III and Protein C. They emphasized the advances in recombinant...