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Designed as a basic reference for researchers in a wide variety of disciplines, this book discusses plant transformation techniques, the generation of transgenic plants, and the engineering of plant viruses to produce vaccine proteins or peptides. It addresses the basis of mucosal immunity using plant-based oral vaccines, organelle targeting for vaccine production, and the role of glycosylation in plant-made mammalian proteins. It also considers vaccine production in entire crops or in large batch cell suspension cultures as well as the development of clinical trials. The book concludes...

Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been made with respect to the development of vaccines, antibodies, and other therapeutic proteins. Biopharmaceuticals in Plants: Toward the Next Century of Medicine provides a comprehensive survey of all major aspects of the development and production of plant-made biopharmaceuticals.

Accompanied by an exhaustive...