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This volume is a multi-disciplinary characterization of the somatosensory system - a field that has experienced revolutionary changes in recent years through the accumulation of basic and clinical data. For example, the discovery of the interaction between the nervous system and the immune system has changed our view on the development of inflammatory diseases, while the cloning of genes encoding different trophic factors boosted studies revealing profound changes in the regeneration of neurones, and the induction of changes in phenotype.

According to the Institute of Medicine (IOM) and U.S. Food and Drug Administration (FDA), "developing new scientific approaches to detecting, understanding, predicting, and preventing adverse events was a critical path to the future of drug safety. This book brings together a collection of state-of-the-art chapters, written by experts in the drug safety field. It provides information on the present knowledge of drug side effects and their mitigation strategy during drug discovery, gives guidance for risk assessment, and promotes evidence-based toxicology. Each specific area of toxicology...