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The most well-known type of neurodegenerative dementia is Alzheimer's disease (AD) in elderly, an age-dependent neurodegenerative disease, proceeds at stages from mild, moderate to severe and gradually destroys the brain. Advancing age, age related diseases such as cardiovascular disease, diabetes, obesity and cancer, head trauma and exposure to heavy metals such as Al, cupper, iron and zinc are the major cause for AD. The current study was designed to explore the potent role of Salvia triloba, Piper nigrum, Ruta graveolens and Pegenum harmala in management of neuroinflammatory insults...

Inhalant abuse is the deliberate inhalation of vapor of the inhalants with the intention to alter one's consciousness. Inhalant abuse can result in serious organ system dysfunction and CNS disorder or even sudden death. The present study focuses on evaluating the role of treatment with different neutracenticals including hormones (melatonin), amino acids (tyrosine and tryptophan) and vitamins (folic acid and vitamin B12) against gasoline, perchloroethylene or toluene-induced neurodegenerative damage in adult male rats. The present result revealed that inhalation of gasoline, perchloroethylene...