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Die Geburt einer selbststandigen Pharmakologie in Freiburg im Breisgau lasst sich auf den Tag genau datieren: Am 12. Marz 1907 wurde die bis dahin bestehende Personalunion - die Pharmakologie wurde zusammen mit der Medizinischen Poliklinik und der Kinderheilkunde durch nur einen Ordinarius vertreten - aufgelost. Das Pharmakologische Institut Freiburg ist also eines der alten im deutschen Sprachbereich, allerdings sechzig Jahre junger als das weltweit alteste in Tartu, Estland.

Dies Buchlein erzahlt seine bald hundertjahrige Geschichte, gegliedert nach den Lehrstuhlinhabern,...

It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This includes a discussion of presynaptic calcium channels, the core proteins of the secretory machinery, and the actions of clostridial toxins and a -latrotoxin, famous for their potency as well as their crucial role in the elucidation of the steps of exocytosis. In the book's second part, the...

It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This includes a discussion of presynaptic calcium channels, the core proteins of the secretory machinery, and the actions of clostridial toxins and a -latrotoxin, famous for their potency as well as their crucial role in the elucidation of the steps of exocytosis. In the book's second part, the...