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This manual provides insights into clinical and laboratory techniques used in assisted human reproduction, for example hormone therapy, in vitro fertilization, diagnostic and microsurgical techniques, cryoconservation, oocyte maturation etc.. Detailed information is given on the practical clinical value of the methods, as well as on their applications in basic research. This comprehensive manual covers the state of the art and prospects for future developments in assisted reproduction. The book is thus a quick and precise guide for clinical gynecologists and specialists in reproductive...

Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of these new inhibitors are under test as potential anti-inflammatory drugs. During the past five years, molecular biology has revealed a superfamily of these phosphodiesterase isoenzymes. This book summarizes the present state of knowledge, as well as giving a comprehensive description of the compounds...