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This work aims to provide an insight of the sources and level of work stress present in the business organizations operating in Lahore, a metropolitan city of Pakistan. Differences among demographic groups in work stress experiences are also investigated. Individuals from management positions participated in this study. Data is collected from private sector organizations by using survey method. Six factors namely role ambiguity, role conflict, quantitative role overload, qualitative role overload, career development, and responsibility for others as identified by literature as potential...

Structure Prediction is one of the most important aspects of Structural Bioinformatics, Protein Docking and Drug Designing. The current study is performed on MTHFR enzyme. It plays an important role in folate and homocysteine metabolism by catalyzing the conversion of 5,10-methylenetetrahydrofolate to 5- methyltetrahydrofolate, used for homocysteine remethylation to methionine. MTHFR mutations have been found in a large number of diseases. However, the structure of MTHFR is still unknown, thereby limiting the understanding of structure function relationship to the diseased state....

HCV, a major cause of liver disease worldwide, is frequently resistant to the antiviral interferon- therapy, being the only approved treatment available. It has been investigated recently that interleukin-8 (IL-8) induced by HCV partially inhibit the IFN- therapy. Therefore we aimed to prospectively utilize the baseline IL-8 levels in the HCV infected serum and predict its role in sustained virological response (SVR) to IFN- + ribavirin therapy, in chronic HCV patients. Fifteen normal volunteers and 110 HCV patients were enrolled in this study. Their baseline IL-8 levels were determined by...