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This research is regarding bone turnover and its association with vitamin D blood levels in adult females. To date, this is the first study exploring the bone health status of apparently healthy adult females residing in Pakistan measuring bone turnover marker using NTx along with 25OHD and iPTH in blood. The highlighted findings of the research are high bone turnover as depicted by levels of serum NTx. Increased serum NTx is reported in 40.5% of the study population. Bone turnover is high among apparently healthy adult females regardless of vitamin D status. This high bone turnover is one of...

Fibroblast growth factor 23 (FGF-23), is recently discovered phosphaturic substance. It releases from bone osteocytes and plays a key role in the physiological regulation of phosphate metabolism. Excessive action of FGF23 results in several hypophosphatemic diseases characterized by impaired renal tubular phosphate reabsorption. In contrast, deficient action of FGF23 causes familial hyperphosphatemic tumoral calcinosis with enhanced renal tubular phosphate reabsorption. We carried out this study to gain knowledge about the current status of FGF-23 levels in our population and its relationship...