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Based in part on the life of baseball legend Ty Cobb, this book belongs in the pantheon of great baseball novels.

John Barr is the kind of player who isn't supposed to exist anymore. An all-around superstar, he plays the game with a single-minded ferocity that makes his New York Mets team all but invincible. Yet Barr himself is a mystery with no past, no friends, no women, and no interests outside hitting a baseball as hard and as far as he can. Not even Ellie Jay, the jaded sportswriter who can out-think, out-drink, and out-write any man in the press box. She wants to think she...

They came by boat from a starving land--and by the Underground Railroad from Southern chains--seeking refuge in a crowded, filthy corner of hell at the bottom of a great metropolis. But in the terrible July of 1863, the poor and desperate of Paradise Alley would face a new catastrophe--as flames from the war that was tearing America in two reached out to set their city on fire.

A literary tour de force, a magnificent chronicle of a remarkable era and a place of dreams

In a stunning work of imagination and memory, author Kevin Baker brings to mesmerizing life a vibrant, colorful, thrilling, and dangerous New York City in the earliest years of the twentieth century. A novel breathtaking in its scope and ambition, it is the epic saga of newcomers drawn to the promise of America--gangsters and laborers, hucksters and politicians, radicals, reformers, murderers, and sideshow oddities--whose stories of love, revenge, and tragedy interweave and shine in...

The Rev. Jonah Dove is the son of a legendary Harlem minister, and a man troubled in both mind and spirit. He feels himself unworthy and incapable of taking up the burden of running his church from the larger-than-life figure who is his father. He is haunted both by his own, shameful history of "passing" as a white man in college, and by the prospects for his people in the harsh, new, racist age he fears the world is entering. Malcolm Little -- better known as Malcom X -- is a teenage hustler from Lansing, Michigan by way of Boston, a young man on the make, trying always to be something...

The classical novel (and basis for the acclaimed film) now in a new edition

Introduction by Kevin Baker

The Natural, Bernard Malamud's first novel, published in 1952, is also the first--and some would say still the best--novel ever written about baseball. In it Malamud, usually appreciated for his unerring portrayals of postwar Jewish life, took on very different material--the story of a superbly gifted "natural" at play in the fields of the old daylight baseball era--and invested it with the hardscrabble poetry, at once grand and altogether believable, that runs...

Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system sodium channels and reviews why sodium channel sub-types are potentially important drug targets in the treatment of pain. The roles of sodium channels in dental and visceral pain are also addressed. The emerging role of sodium channel Nav1.3 in neuropathic states is another important theme.

Authors from the pharmaceutical...