Lead: Its Effects on Environment and Health

ISBN-13: 9783110441079 / Angielski / Twarda / 2017 / 596 str.

Katsuyuki Aoki;Michael Aschner;Jay T. Cullen

Opis

Volume 17 of the series Metal Ions in Life Sciences will be devoted to "Lead: Its Impact on Environment and Health." The topics to be covered are evident from the tentative Table of Contents. The scheduled 15 chapters will be written in an authoritatively and timely manner by internationally recognized experts. Chapter 1 will be setting the scene by providing those aspects of the chemistry of lead which are important for its impact on life and the environment. The biogeochemistry of lead, its anthropogenic release into the environment, its cycling, speciation in the atmosphere, in waters, soils, and sediments will be covered and of course, the analytical tools employed will be described; this includes fluorescent sensors, but also leadzymes and DNAzymes ... and the use of lead in batteries, etc. Its determination in blood, plasma, serum, and urine as well as in hair, saliva, and various tissues is certainly also an important topic. The properties of lead complexes formed with amino acids, peptides, nucleobases, nucleotides, and other ligands of biological relevance will be summarized for the solid state and for aqueous solutions as well. All this is important for obtaining a coherent picture about the interrelations between lead and biosystems. Other aspects are the toxic actions of lead on mammalian organs, including the effects on renal cells ... and bones, of course ... and the role that metallothioneins play in lead(II) detoxification. The toxicity of lead for plants is also covered and the lead-induced changes in the phosphorylation of PSII proteins are considered. All this and more will be dealt with in MILS-17.

Recenzje

"(...) The well-balanced and comprehensive selection of aspects makes it the most valuable source of information on the present state of research in the field. This volume is an important addition to every library of a chemistry or biochemistry research institution, and it will serve as an essential reference work for every researcher in the field of metals in biology."
Bernt Krebs in: Coordination Chemistry Reviews 361 (2018) 164-165

"(...) the three Sigels-Helmut, Astrid, and Roland-continuing their extraordinary service to the bioinorganic chemistry community. Volume 17 provides a snapshot of where we are in our understanding of the bioinorganic chemistry of lead and points to areas where more work is needed. It also provides a staggering number of references that the interested reader can use to deepen their knowledge of whatever facet of lead chemistry they want to pursue. As the editors state in the preface, the volume 'is rich on specific information, but it provides also basic insights that should help to promote further our understanding of the unique role which this toxic metal plays in the environment and in human health.'"
Rachel Narehood Austin in: Journal of Inorganic Biochemistry 176 (2017) 181-182

"(...) Volume 17 of Metal Ions in Life Sciences is the most current source of information on the fundamental biochemistry of lead, and a useful and timely summary of its impact on human health and the environment. It should be widely available and frequently consulted."
Dean Wilcox in: Inorganica Chimica Acta 474 (2018) 117

"(...) This book will undoubtedly arouse the reader's fresh attention to the toxic metal and deepen the understanding of its chemical properties, toxicity and underlying chemistry, and biological and global environmental effects. It is strongly recommended not only for researchers in relevant fields and those interested in the structure, function, and toxicity of metals but also for students aiming at bioinorganic, biogeochemical, biological, environmental, and related fields of chemistry."
Osamu Yamauchi in: Transition Metal Chemistry 42 (2017) 275-277

"(...) The book presents a comprehensive review of the present knowledge of the role of lead in humans, flora and fauna, and the environment. It is well organized and well written. (...)"
Hubert Schmidbaur in: Zeitschrift für Naturforschung B 72 (2017) 527-528

Spis treści

From the Contents:

- The Bioinorganic Chemistry of Lead
- The Biogeochemistry of Lead, Its Release to the Environment, and Its Speciation
- Determination of Lead in Biological Samples
- Solid State Structures of Lead Complexes with Relevance for Biological Systems
- Lead(II) Complexes of Amino Acids, Peptides, and Other Related Ligands of Biological
Interest
- Lead(II) and Metallothioneins
- Lead(II) Binding in Natural and Artificial Proteins
- Complex Formation of Lead(II) with Nucleotides and Their Constituents
- Nucleic Acid-Lead(II) Interactions (including leadzymes)
- Tetraalkyllead(IV) Derivatives: Their Use in Technology and Their Impact on the Environment
- Lead Toxicity in Plants
- Toxicology of Lead and Its Damage to Mammalian Organs

O autorze

Helmut und Astrid Sigel, University of Basel, Switzerland. Roland K. O. Sigel, University of Zürich, Switzerland.