Wyniki wyszukiwania:

G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of physiological and pathophysiological conditions. GPCRs or GPCR-dependent signalling pathways are the targets of a very large number of therapeutically useful drugs. Detailed knowledge about the molecular structure of GPCRs should therefore pave the way for the design of novel drugs with increased efficacy and specificity.

This volume provides a concise, up-to-date presentation of methods (including molecular genetic, biochemical, and...

Ongoing advances in science and engineering enable mankind to design and operate increasingly sophisticated systems. Both their design and operation require the understanding of the system and its interaction with the envir- ment. This necessitates the formalisation of the knowledge about the system by models. A major issue is what kind of model is best suited for a given task. This book is about the supervision of continuous dynamical systems. Such systems are typically described by di?erential equations. However, this does notautomaticallymeanthatdi?erentialequationsarepropermodelsforso-...