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In the highly industrialized countries about 20% of all workers have to do shiftwork including nightshifts. Furthermore about half of the shift workers also have to work at weekends (so-called continuous shiftwork). There are social, economic or technological reasons for shiftwork. Many shiftworkers complain of disturbances of wellbeing, sleep, appetite and performance whereas only a few persons have to expect special illnesses like ulcera of the gastric intestinal system. The main problem of shiftwork is the question of adaptation of the circa dian rhythms of physiological functions to the...