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Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is intended for all those using or wanting to learn more about computational methodologies in epigenetic drug discovery, including molecular modelers, informaticians, pharmaceutical scientists, and medicinal chemists.

With a better understanding of different molecular modeling and...

As the new millennium opens, the greatest generation draws to a close. The December of their years are closing fast. Soon the men and women who lived through the war will only be memories.

The Last Reunion depicts the experience and turmoil that they encountered through the years by using their unit (Seventy-Seventh Infantry Division) reunions as milestones.

The central character is a platoon sergeant who leads them through the war years and remained close to certain members of his platoon and squad.

The story begins with the sergeant's death and the subsequent...

As the new millennium opens, the greatest generation draws to a close. The December of their years are closing fast. Soon the men and women who lived through the war will only be memories.

The Last Reunion depicts the experience and turmoil that they encountered through the years by using their unit (Seventy-Seventh Infantry Division) reunions as milestones.

The central character is a platoon sergeant who leads them through the war years and remained close to certain members of his platoon and squad.

The story begins with the sergeant's death and the subsequent...

Inquiry into the nature and purpose of language has long been a central concern of Western philosophy, within both the analytic, Anglo-American tradition, and its Continental counterpart. Language: Key Concepts in Philosophy explains and explores the principal ideas, theories and debates in the philosophy of language, providing a clear and authoritative account of the discipline. The text covers the work on language of the major philosophers in both traditions, including Frege, Wittgenstein, Austin, Quine, Davidson, Heidegger, Gadamer, Derrida and Butler. The book equips readers with the...