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By focusing on the cellular mechanisms that underlie ontogeny, phylogeny and regeneration of complex physiologic traits, Evolution, the Logic of Biology demonstrates the use of homeostasis, the fundamental principle of physiology and medicine, as the unifying mechanism for evolution as all of biology. The homeostasis principle can be used to understand how environmental stressors have affected physiologic mechanisms to generate condition-specific novelty through cellular mechanisms.

Evolution, the Logic of Biology allows the reader to understand the vertebrate...

Cellular-molecular approach to evolution has led to radical changes in our understanding of biologic principles ranging from the Cell, to the Life Cycle, Development, Homeostasis, Senescence/Aging, Heterochrony, Pleiotropy, Phenotype, and perhaps the purpose of life itself. Much of this new way of thinking about biology and medicine emanates from experimental evidence for epigenetic inheritance.  This leads one to question whether our unicellular state is the actual primary level of selection.

One particular system that is now recognized as being under the auspices of...

The teaching of evolutionary biology in medical schools is becoming more and more popular, yet Darwinian principles and evidence-based medicine remain poorly integrated. Nevertheless, there is a great advantage to this integration: by acquiring an understanding of the underlying principles, the student will find that biology becomes predictive and not just descriptive. The approach the authors take in this book offers this opportunity, making it 'user friendly' for current and future students of physiology, medicine, pathophysiology, epidemiology, etc., etc. By taking the...