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This study looks at the way the products of arachidonic acid metabolism are active both in normal and abnormal immune responses. While some of the fundamental issues such as whether lymphocytes are capable of producing prostaglandins and leukotrienes are still hotly debated, the evidence is overwhelming that many specific immunological problems and disease states are associated with alterations in the normal balance of arachidonic acid metabolism. This book provides a review of the history and chemistry of the arachidonic acid cascade as well as an exhaustive survey of the literature...

Colorado's San Juan Mountains are home to some of the most historic, and notorious, gold and silver mining towns in the West: Ouray, Silverton, Telluride, and Creede. For five centuries, the San Juans were the summer home to the Ute Indians. They were explored and claimed by Spaniards 250 years ago, and it has only been 150 years since they were entered and permanently settled by European Americans.

Probably above all else, the San Juan Mountains' legacy will be tied to the mining camps and towns that littered their terrain. The 1859 Pikes Peak gold rush brought the prospectors, followed by...

In the history of the San Juan mining region, Duane Smith's text and John Ninnemann's photographs offer a glimpse into the lives of towns that sprang up in remote canyons and mountain plateaus in southwestern Colorado and the settlers who attempted to recreate the eastern communities they had left behind.

Eighty-five black-and-white photos and accompanying essays share the beauty of the canyons and mesas of the Colorado Plateau and the history of the resourceful inhabitants.