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"Crucible of Science" is the story of a unique laboratory at Washington University in St. Louis, and of Carl and Gerty Cori, the biochemists who established it. Carl and Gerty met and married at medical school in Prague in the 1920s. After graduation, they immigrated to the U.S. to escape deteriorating conditions in Europe. Carl soon received an offer from Washington University to become Pharmacology Chair, and the couple settled in St. Louis. Not only did both Coris go on to win the Nobel Prize, the laboratory they established at the University has since produced some of the most outstanding...

Lipids traditionally have been viewed as serving two functions: to form cellular membranes and to serve as energy stores. During the last two decades, a new role for lipids has taken center stage: lipids can act as signalling molecules. This book deals with a variety of lipids that have been shown to be messengers. Leading scientists explore all known lipid classes except steroid hormones. Researchers and educators in biochemistry as well as in molecular and cellular biology will appreciate this volume.