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The field of oligonucleotide therapeutics research is ripe with the prospect of new discoveries. In "Therapeutic Oligonucleotides: Methods and Protocols," a selection of established and emerging methods for the application of oligonucleotides as therapeutics are presented, all providing the tools needed to inspire great changes in the field. Divided into twenty-one chapters, this detailed volume meticulously describes vital protocols for optimizing and improving cell uptake, such as photochemical internalization, modified cell penetrating peptides, antibody conjugates, and nanoparticles....

The articles in this collection cover financial subjects ranging from the first introduction computers to mathematical techniques into finance, through the oil crisis years, to the valuation of brands, intellectual property and goodwill. Each article provides a fascinating insight both into the subject concerned and into contemporary thinking at the...