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This book compiles and reorganizes previously published research to give readers a clear overview of how living systems respond to hydrostatic pressure a force present from the deepest oceans to the human body. Although scientists have recognized its importance for decades, many questions remain. By bringing together work from across the field, this volume provides a comprehensive look at both the physical forces involved and the biological processes they influence.

The central theme is how cells sense pressure and convert it into biological signals, a process known as Mechan...

Mechanobiology--the study of the effects of mechanical environments on the biological processes of cells--has evolved from traditional biomechanics via the incorporation of strong elements of molecular and cell biology. Currently, a broad range of organ systems are being studied by surgeons, physicians, basic scientists, and engineers. These mechanobiologists aim to create new therapies and further biological understanding by quantifying the mechanical environment of cells and the molecular mechanisms of mechanically induced pathological conditions.

To achieve these goals,...

Mechanobiology-the study of the effects of mechanical environments on the biological processes of cells-has evolved from traditional biomechanics via the incorporation of strong elements of molecular and cell biology. Currently, a broad range of organ systems are being studied by surgeons, physicians, basic scientists, and engineers. These mechanobiologists aim to create new therapies and further biological understanding by quantifying the mechanical environment of cells and the molecular mechanisms of mechanically induced pathological conditions.

To achieve these goals,...