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The cutting-edge development of using a computational design approach as a means of engineering proteins with novel functions has led to widespread usage of computational analysis in protein engineering at large. However, because the structure and function of protein molecules are coupled at the molecular level, many critical questions are left unanswered and many of the intricate design rules unclear. This book furthers understanding in this complex design area by using lucid description of computation's role in protein engineering and tracing the history of protein design. In so doing, it...

The essays in Visualizing the Past in Italian Renaissance Art address a foundational concept that was as central to early modern thinking as it is to our own: that the past is always an important part of the present. Written by the friends, students, and colleagues of Dr. Brian Curran, former professor of Art History at the Pennsylvania State University, these authors demonstrate how reverberations of the past within the present are intrinsic to the ways in which we think about the history of art. Examinations of sculpture, painting, and architecture reveal the myriad ways that history has...