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Lee Soyeon, Myeong-ok, and Yeonjeong are all mothers in their mid-fifties. And they ve had it. They can no longer bear the dead weight of their partners or the endless grind of menial jobs where their bosses control everything, down to how much water they can drink. Although Lee Soyeon divorced her husband years ago after his gambling drove their family into bankruptcy, she finds herself in another tired and dishonest decade-long relationship with Jongseok, a slimy waiter at a nightclub. Meanwhile, Myeong-ok is having an illicit affair with a younger man, and Yeonjeong, whose husband suffers...

In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic information was administered to elicit an immunological response. Once it was observed that plasmid DNA delivered in vivo led to production of an encoded transgene (1), two ground-breaking studies demonstrated that immunological responses could be generated against antigenic transgenes via plasmid DNA...

In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic information was administered to elicit an immunological response. Once it was observed that plasmid DNA delivered in vivo led to production of an encoded transgene (1), two ground-breaking studies demonstrated that immunological responses could be generated against antigenic transgenes via plasmid DNA...