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Anti-Angiogenic Cancer Therapy provides information on the process of angiogenesis and its role in tumor growth and metastasis. This book examines angiogenesis inhibitors under clinical investigation as well as early agents used in preclinical studies. It discusses the unique aspects of targeting and inhibiting angiogenesis and the challenges associated with clinical development of angiogenesis including trial design and surrogate marker endpoints. With information on the design and execution of preclinical studies, the application of genomics and angiogenesis, and the regulatory approval...

The field of solid tumor oncology is changing at an astonishing rate. To learn about new developments, generate fresh research perspectives, and then integrate these advancements into clinical practice is a daunting challenge confronting all who work in the oncology arena. The onset and rapid deployment of Internet capacities worldwide has created a mileau of global and instantaneous information access. The task of staying current is - coming even more challenging, and in some ways, more difficult to accomplish. Against this information pressure backdrop, how can yet more didactic material...

In 74 chapters, Gastrointestinal Oncology brings together a diverse group of specialists to provide the most authoritative, up-to-date and encyclopedic volume currently available on the subject. The first part of this text introduces a series of concepts and topics taht are important to gastrointestinal malignancies in general. These topics include epidemiologic principles, prevention, screening, familial GI cancers, developmental and molecular biology, pathobiology, general therapeutic principles, emerging therapies, and palliative care. The second part of the book covers each of...