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This book is devoted to the state of the art, pitfalls and perspectives in the diagnosis and treatment of mesothelioma – a peculiar malignant tumour arising from mesothelial cells that line the pleura, the pericardium and the peritoneum. Mesothelioma is known for its strong association with asbestos exposure, difficult surgical treatment and dismal prognosis. However, recent years have yielded significant discoveries on, for example, germline mutations in BAP1 gene coding BRCA1-associated protein 1, the pathogenetic role of inflammation, and innovative treatment approaches such as immune...

and #60;i and #62;Challenges in Pleural Pathology - Diagnostics, Treatment and Research and #60;/i and #62; is devoted to the state-of-the-art, pitfalls, and perspectives in the diagnostics and treatment of pleural pathology, ranging from effusions, inflammation, and fibrosis to tumors. It summarizes the classic concepts and innovations in the diagnosis, treatment, and scientific studies of pleural pathology, resulting in a clinically oriented reference as well as a source of ideas for relevant clinical and basic research. Chapters address pleural pathology in childhood, pleural tuberculosis,...