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This new edition of Animal Models in Cardiovascular Research describes historical and recent advances in our understanding of the cardiovascular system from studies conducted in a variety of animal models. Since the last edition we have witnessed an explosion in the use of both congenic and transgenic animals. The use of specific knock-in and knock-out transgenic models has resulted in an avalanche of genetic, molecular and protein-based information that, potentially, could result in an amazing new array of treatment and management options. However, the results of these studies...

"Introduction to Embedded System Design Using Field Programmable Gate Arrays" provides a starting point for the use of field programmable gate arrays in the design of embedded systems. The text considers a hypothetical robot controller as an embedded application and weaves around it related concepts of FPGA-based digital design. The book details: use of FPGA vis-a-vis general purpose processor and microcontroller; design using Verilog hardware description language; digital design synthesis using Verilog and Xilinx(r) SpartanTM 3 FPGA; FPGA-based embedded processors and peripherals;...

This textbook provides a comprehensive introduction to the main fundamental problems of concern to developers of middleware for mobile environments. Each chapter is structured as a self-contained tutorial presenting an overview of a specific topic.

As an annual of the five leading German institutes working in the field of the analysis of spatial development and policies, this book will present discussions about the guiding principles for spatial development being a virulent new approach to the future development of Germany in spatial differentiation. The papers will discuss these guiding principles theoretically and empirically.

A model-based approach to the design and implementation of Computational Sensor Networks (CSNs) is proposed. This high-level paradigm for the development and application of sensor device networks provides a strong scientific computing foundation, as well as the basis for robust software engineering practice. The three major components of this approach include (1) models of phenomena to be monitored, (2) models of sensors and actuators, and (3) models of the sensor network computation. We propose guiding principles to identify the state or structure of the phenomenon being sensed, or of the...