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While knowledge-intensive environments encourage and foster new ideas for products, services, production methods and business models, they also entail high levels of risk derived from the fast and dynamically changing nature of technology. This Handbook explores the new theoretical frameworks that are needed to cope with the growing relevance of techno-entrepreneurship initiatives globally. Demonstrating that techno-entrepreneurship and its ecosystems create opportunities across national borders, this Handbook also shows how they proactively shape their business environment and engage in...