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Stroke should be thought of as a syndrome, or collection of disease processes, rather than a single disease. It is characterised by restriction of blood flow to the brain and is responsible for imposing a very significant burden on healthcare systems, accounting for more than four million deaths per year. It can be directly linked to the majority of adult neurological disability as well as contributing to vascular dementia, the second most common cause of dementia after Alzheimer's Disease. Despite its importance on a population basis, research into the genetics of stroke has lagged behind...