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The Maternal-to-Zygotic Transition provides users with an expert accounting of the mechanisms and functions of this transition in a range of animal and plant models.

The book provides critical information on how maternal gene products program the initial development of all animal and plant embryos, then undergoing a series of events, termed the maternal-to-zygotic transition, during which maternal products are cleared and zygotic genome activation takes over the developmental control.

• Maternal gene products program the initial development of all...

Edward B. Lewis' science is the bridge linking experimental genetics as conducted in the first half of the twentieth century, and the powerful molecular genetic approaches that revolutionized the field in its last quarter. His Nobel Prize winning studies founded the field of developmental genetics and laid the groundwork for our current understanding of the universal, evolutionarily conserved strategies controlling animal development. A lesser-known aspect of Lewis' canon is the pioneering studies he carried out on ionizing radiation and human cancer. In doing so, he was propelled into a...