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Linear Systems: Non-Fragile Control and Filtering presents the latest research results and a systematic approach to designing non-fragile controllers and filters for linear systems. The authors combine the algebraic Riccati technique, the linear matrix inequality (LMI) technique, and the sensitivity analysis method to establish a set of new non-fragile (insensitive) control methods. This proposed method can optimize the closed-loop system performance and make the designed controllers or filters tolerant of coefficient variations in controller or filter gain matrices.

More and more, the advanced technological systems of today rely on sophisticated control systems designed to assure greater levels of safe operation while optimizing performance. Rather than assuming always perfect conditions, these systems require adaptive approaches capable of coping with inevitable system component faults. Conventional feedback control designs do not offer that capability and can result in unsatisfactory performance or even instability, which is totally unacceptable in complex systems such as aircraft, spacecraft, and nuclear power plants where safety is a paramount...

Linear Systems: Non-Fragile Control and Filtering presents the latest research results and a systematic approach to designing non-fragile controllers and filters for linear systems. The authors combine the algebraic Riccati technique, the linear matrix inequality (LMI) technique, and the sensitivity analysis method to establish a set of new non-fragile (insensitive) control methods. This proposed method can optimize the closed-loop system performance and make the designed controllers or filters tolerant of coefficient variations in controller or filter gain...

Recent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a critical requirement. There is an unprecedented urgency for aspiring and practicing clinicians to become trained on how to interpret data from pharmacogenomic testing in preparation for the future of healthcare i.e., personalized medicine.