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Peptides as Immunogens
ISBN: 9783642714429 / Angielski / Miękka / 2011 / 86 str. Termin realizacji zamówienia: ok. 20 dni roboczych. The humoral response of the immune system to a foreign antigen usually requires the recognition of two antigenic determinants. The one, called the carrier, is recognized by T-Iymphocytes, the other, called the hapten, by B-Iympho- cytes. As a consequence, T - and B-Iymphocytes proliferate, B-Iymphocytes produce hapten-specific antibodies, and the system develops memory to the antigens. It was long thought that antigens would form a bridge to mediate the cooperation of T - and B-Iymphocytes. However, it now appears that antigens are broken down to fragments which then act as carrier...
The humoral response of the immune system to a foreign antigen usually requires the recognition of two antigenic determinants. The one, called the car...
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391,77 zł |
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The Role of Nitric Oxide in Physiology and Pathophysiology
ISBN: 9783642791321 / Angielski / Miękka / 2011 / 90 str. Termin realizacji zamówienia: ok. 20 dni roboczych. Nitric Oxide (NO) an endogenous free radical, has been shown recently to mediate several important biological effects. It plays a neuro-transmitter like role in vascular endothelium, a scond-messenger role in N-methyl-D-aspartate (NMDA) responsive neurons in the central nervous system (CNS), a neurotoxic role after its release from these neurons, and a cytotoxic role after its release by macrophages.
This volume reviews among other topics the basic chemistry and physical properties of S-nitrosothiols (RS-NO) and their biochemical mechanisms of action, NO synthase isozymes, NO synthase... Nitric Oxide (NO) an endogenous free radical, has been shown recently to mediate several important biological effects. It plays a neuro-transmitter li...
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195,87 zł |
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Images of Biologically Active Structures in the Immune System: Their Use in Biology and Medicine
ISBN: 9783642706776 / Angielski / Miękka / 2011 / 142 str. Termin realizacji zamówienia: ok. 20 dni roboczych. The diversity of antigen-binding structures of antibody molecules is so vast that every conceivable antigen can be bound by an antibody molecule within the immune system. This is true even for the antigen binding sites of antibodies called idiotypes, which are bound by complementary bind- ing sites of other antibodies called anti-idiotypes. Thus, anti-idiotypes are structural homologues of antigens. These idiotypic-anti-idiotypic interactions constitute a network within the immune system. Since one lymphocyte produces only one type of antibody molecule, this network is in fact a network of...
The diversity of antigen-binding structures of antibody molecules is so vast that every conceivable antigen can be bound by an antibody molecule withi...
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391,77 zł |
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Borna Disease
ISBN: 9783642786204 / Angielski / Miękka / 2013 / 138 str. Termin realizacji zamówienia: ok. 20 dni roboczych. Borna disease was first described over 200 years ago, in what is now Southeastern Germany, as a fatal neurologic affliction of horses and was considered a curiosity for many decades. The causative agent was unknown, and the animal species infected in nature were limited to horses and sheep. Today, as described in this volume, the host range has extended to all warm-blooded animals, the genes and proteins of the virus have been identified, and many of the mechanisms responsible for behavioral disturbances are understood. Serologic studies suggest that BDV or related agents are likely to play a...
Borna disease was first described over 200 years ago, in what is now Southeastern Germany, as a fatal neurologic affliction of horses and was consider...
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cena:
195,87 zł |
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DNA Vaccination/Genetic Vaccination
ISBN: 9783642804779 / Angielski / Miękka / 2011 / 198 str. Termin realizacji zamówienia: ok. 20 dni roboczych. Genetic / DNA immunization represents a novel approach to vaccine and immune therapeutic development. The direct injec- tion of nucleic acid expression cassettes into a living host results in a limited number of its cells becoming factories for production of the introduced gene products. This host-inappropriate gene expression has important immunological consequences, resulting in the specific immune activation of the host against the gene- delivered antigen. The recent demonstration by a number of laboratories that the induced immune responses are functional in experimental models against...
Genetic / DNA immunization represents a novel approach to vaccine and immune therapeutic development. The direct injec- tion of nucleic acid expressio...
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cena:
391,77 zł |
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Lyssaviruses
ISBN: 9783642784927 / Angielski / Miękka / 2011 / 352 str. Termin realizacji zamówienia: ok. 20 dni roboczych. Lyssaviruses are the etiological agents of rabies, one of the oldest documented and feared maladies in medical history. The last century has been particularly fruitful in regard to progress in Iyssavirus phylogenetic affinities, diagnostics, pathogenesis, molecular virology and epidemiology, pro- phylaxis and control. Yet, despite these academic and practical advances in research, the age-old horror evoked by rabies is still very real, with only four documented human recoveries once symptoms are realized. After decades of intense scrutiny and four recent books describing rabies and its viral...
Lyssaviruses are the etiological agents of rabies, one of the oldest documented and feared maladies in medical history. The last century has been part...
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cena:
391,77 zł |
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Transacting Functions of Human Retroviruses
ISBN: 9783642789311 / Angielski / Miękka / 2014 / 243 str. Termin realizacji zamówienia: ok. 20 dni roboczych. The genome of retroviruses contains three major coding regions for virion proteins, gag, pol and env. Gag encompasses information for nonglycosylated viral proteins that form the matrix, the capsid and the nucleoprotein structures. From pol derive reverse transcriptase and integrase, and env codes for the surface glycoproteins of the virion which consist of a transmembrane and a surface domain, linked by disulfide bonds. A viral protease is derived eitherfrom the gagorfrom the pol coding region, depending on the virus. Simple retroviruses contain only this elementary gag, pol, and env coding...
The genome of retroviruses contains three major coding regions for virion proteins, gag, pol and env. Gag encompasses information for nonglycosylated ...
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cena:
391,77 zł |
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