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Hydroxyapatite(HA) used for bone replacement is one of the most active areas of biomaterials research currently.It has been used for the last 30 years due to its excellent biocompatibility,osseoconduction and osseointegration.Many modifications have been done to develop a stronger,tougher and biocompatible HA due to pure HA is brittle.Our scientists have made this value added HA that is less brittle compared to pure HA.This study was to evaluate the genotoxicity of the value added HA using Bacterial Reverse Mutation Assay/Ames test.Mutated Salmonella typhimurium and Escherichia coli strains...