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This book includes various spectrophotometric and chromatographic methods for eprosartan and its formulation. Simple, first derivative and difference spectrophotometric methods for eprosartan are developed and validated. HPLC method is developed and validated for estimation of eprosartan in tablets, plasma and stability samples. HPTLC method is also developed and validated for eprosartan alone and in combination with hydrochlorthiazide.

This book includes introduction to HPLC and HPTLC technique for estimation of drugs and ICH guidelines parameters for the method validation. Apart from this it contains HPLC and HPTLC method for the estimation of balofloxacin in bulk and tablets. These methods are stability indicating.Force degradation study showed that balofloxacin moderately degradable in acidic and oxidative conditions and relatively stable to alkaline, neutral hydolysis, thermal and photolytic stress.

The book describes the preparation and evaluation of orally fast dissolving film of Domperidone- an anti emetic drug. As Domperidone possess very less water solubility, preparation of rapidly dissolving film is a challenge. Hence, in order to increase the solubility, solid dispersion approach is utilized and it is prepared using beta- cyclodextrin as a carrier. Solid dispersion are prepared in various molar ratio of Drug: Carrier and evaluated. Based on evaluation, the optimized solid dispersion is selected and utilized further for the preparation of films. Suitable film forming polymer was...