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This work provides an insight into the complex interaction among the pathways regulating obesity, cardiovascular health, diabetes, inflammation and metabolism. It also emphasized the thyroid hormones as a key player to address multifaceted metabolic defects in the studied animal model. In this book we also provided working protocols of the biochemical tests used in present work. I hope this book will be helpful to post graduates, professionals and researchers working in the area of Medical, Biomedical, Biotechnology, Biochemistry and other Life Science streams.