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This book proposes a way to radically renew medicine by extending to medicine the concepts of evolutionary biology. The book considers diseases not as unpredictable harmful events but as logical consequences of evolutionary mechanisms. In particular, a large part of the most widespread diseases that afflict modern populations are interpreted as the consequence of discordances (mismatches) between new living conditions and the adaptation of our species. It discusses the basic concepts, as well as diseases deriving from alterations of the genotype and general concepts about diseases deriving...