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In the present investigation,the efficacy Allyl isothiocyanate(AITC)against N-nitrosodiethylamine induced experimental liver carcinogenesis and in human hepatoma cell line (HepG2)were studied.Cell migration inhibition effect of AITC reveal that the drug has a role in delay of cancer progression . The dose dependent protein expression of P53 and Caspase 3 disclose the anticancer potency of the drug AITC.This was confirmed by various biochemical,molecular biological and histopathological examinations as well.

Cadmium is toxic to a wide range of organisms; the main effects are on the growth and reproduction. Dissolved cadmium salts released in drainage water from mines may represent a significant threat to aquatic wildlife. Reproductively active aquatic animals exposed to pollutant stress undergo alterations in their biochemical and physiological functions leading to the disturbed reproductive processes. Biochemical constituents and enzymes are the first detectable / quantifiable responses to environmental changes and can serve as markers for both exposures and effects in organisms. In the edible...

Breast cancer is one of the second most common cancers in the world. Recent research suggest that plant derived drugs are of great interest due to its health benefits not only food substances of plant origin but also for the therapeutic usage to combat against various ailments due to the absence of adverse side effects. In the present investigation, efficacy of diosgenin in mammary carcinoma cell line (MCF-7) and in experimental breast cancer was investigated. Inhibition of MCF-7 cells is likely to be selective apoptotic nature of the compound diosgenin. In addition, diosgenin is very...