Immune Functions of the Vessel Wall

ISBN-13: 9783718658916 / Angielski / Twarda / 1996 / 208 str.

Goran K. Hansson; Peter Libbey; Gordan K. Hansson

Opis

Until recently, the vascular system was perceived as inert, and immunology and vascular biology were seen as unrelated disciplines. However, research has now shown that much of the work of the immune system occurs within the vascular canals and there is constant interaction between the immunocompetent cells and the vessel wall. This volume summarizes the manifold interactions between the endothelium and the immune response system and includes important sections examining the immunopathology involved in various forms of vascular damage, particularly atherosclerosis.

Spis treści

1. The Endothelium as an Antigen Presenting Cell 2. Antigen Presentation by Brain Microvascular Smooth Muscle 3. Vascular Cells Produce and Respond to Cytokines 4. Chemokines in Vascular Pathophysiology 5. Immunopathological Approaches to Clarify the Etiopathogenesis of Systemic Arteritis 6. The Role of Autoimmunity to Myeloid Lyosomal Enzymes in the Pathogenesis of Vasculitis 7. Humoral Immunity and Vascular Injury in the Pathogenesis of Discordant Xenograft Rejection 8. Immune Responses in Atherosclerosis 9. Autoimmunity to Oxidized Lipoproteins 10. The Role of Heat Shock Protein 65/60 in the Initial Immune-Mediated Stages of Atherosclerosis

O autorze

Goran K Hansson