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Stroke remains one of the major causes of death and long-term disability worldwide. Currently, the only approved therapy for the acute treatment of this disease is thrombolysis, a strategy that can only be applied to a small percentage of patients due to its narrow therapeutic window. Unfortunately, during the last years numerous promising drugs that showed neuroprotection in the experimental setting failed to translate into the clinic because of their toxicity or lack of efficacy.

Researchers in the field now face the crucial need to develop effective stroke therapies and...

This book is focused on a clinical-based diagnostic approach of autonomic dysfunctions, highlighting main diagnostic tools and pharmacological and non-pharmacological therapies available nowadays.    The autonomic nervous system (ANS) is a subcomponent of the peripheral nervous system (PNS) and dysfunction of one or more subdivisions of the ANS, when accompanying other diseases, is linked to a worse prognosis of the latter. In some circumstances or when severe, dysfunction of ANS itself results in symptoms and disability.  A myriad of factors can cause autonomic dysfunction and more...