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Aparadigmshiftistakinginraisingstandardsonallaspectsoftissuebankingfrom procurementtoprocessing,fromstoragetoclinicalusage. Anumberofmonographs haveappearedgivingguidanceonGMPandqualitysystemsthatshouldbeadhered to. Therearealsogoodguidelinesonthesigni?canceofthenewregulationsthat havebeenenacted. However there is a signi?cant lack of information on the scienti?c basis and rationaleonwhytissuebankingpracticeshavedevelopedthewaytheyhave. Many ofthemhavedevelopedwithoutmuchvalidationandhavebeeninuseformany years, copied from one tissue bank to another. There are some good articles on...