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Rheumatic inflammatory diseases represent a steadily increasing group of disorders that have considerable social impact through affected patients' worsening quality of life and require engagement in the health field. Among these, rheumatoid arthritis stands as the most frequent pathology, and the hand is the most typical affected area. The incidence of rheumatic arthritis, as indicated by recent epidemiological studies, is bound to undergo a further significant increase in the future. There is, therefore, a need for careful diagnosis of the disease, based on clinical criteria designed by the...

Il moderno approccio terapeutico al paziente affetto da metastasi ha subito, nel corso dell'ultimo decennio, un radicale mutamento. Al noto concetto di diagnosi precoce del tumore primitivo viene ad affiancarsi quello della diagnosi precoce delle metastasi, al fine di intervenire altrettanto tempestivamente con intenti di potenziale radicalita. Inoltre, aumentando la sopravvivenza del malato oncologico, sistematicamente monitorato mediante tecniche di immagine, si e documentato il riscontro in vivo di metastasi anche in sedi differenti da quelle considerate classiche e un estremo polimorfismo...

Modern therapeutic strategies in the last decade have radically changed the approach to the oncologic patient with metastatic disease. Metastases are managed more aggressively and addressed in a multidisciplinary way. This text considers those changes in diagnosis and treatment.