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A New Intramembrane Integrative Mechanism.

It is important to remember how immature the catecholamine field was in the beginning of the 1960 ies. At the CIBA Foundation Symposium on Adrenergic Mechanisms (London) in 1960 Prof. Gaddum stated: "The meeting was in a critical mood and no one ventured to speculate on the relation between catecholamines and the brain" . It was therefore a major breakthrough in the monoamine field when it became possible in the 1960ies with the help of a highly sensitive and specific fluorescence method for the cellular demonstration of catecholamines and 5- hydroxytryptamine, the so called Falck-Hillarp...

This book is the proceedings of an International Wenner-Gren Center Foundation Symposium on "Excitotoxins" held at the Wenner-Gren Center in Stockholm on August 26 and 27, 1982. We are particularly happy that so many of the leading scientists in this field have been able to participate in this symposium. Since the book on "Kainic Acid" appeared in 1978 edited by Dr. McGeers and Dr. John Olney there has been an explosive interest in the research on neuroexcitatory and toxic amino acids. We therefore feIt the time was right to bring the leading experts in this field together by organising a...

This volume covers methodologies, ranging from the molecular level to the network level, used to study receptor-receptor interactions in heteroreceptor complexes inside the central nervous system.